Inheriting Thalassemia

Inheriting Thalassaemia – Alpha & Beta

Fig 1: Alpha Thal Carrier and Non Carrier:

If couples are tested and only one partner proves to be a carrier then there is no danger to their children.

In each pregnancy there is a 1 in 2 chance that the child will carry alpha zero thalassaemia.

FIG 2: Alpha Thal Carrier & Alpha Thal Carrier:

If both partners are carriers then there is a 1 in 4 chance of each pregnancy to produce a child with Alpha Zero thalassaemia major.This is a very serious anaemia that develops in the unborn baby and it can only happen when both parents carry alpha zero thalassaemia.

Genetic counseling is suggested to discuss the several options open for having a healthy family. If after full discussion the couple decides to undertake a pregnancy, the mother can be offered pre-natal testing for the disorder.

FIG 3: Beta Thal Carrier & Beta Thal Carrier:

If couples are tested and one partner proves to be a carrier then there is no danger to their children (same as Fig 1). If both partners are carriers there is a 25% chance of each pregnancy to produce a child with beta thalassaemia major.

Genetic counseling is suggested to discuss the several options open for having a healthy family. If after full discussion the couple decides to undertake a pregnancy, the mother can be offered pre-natal testing for the disorder.

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Free Thalassemia Screening, Free CBC, Free Sugar Testing, Free BP Checkup at Clinical Advisors, Gulshan e Iqbal, Karachi
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February 14, 2019
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