Inheriting Thalassemia

Inheriting Thalassaemia – Alpha & Beta

Fig 1: Alpha Thal Carrier and Non Carrier:

If couples are tested and only one partner proves to be a carrier then there is no danger to their children.

In each pregnancy there is a 1 in 2 chance that the child will carry alpha zero thalassaemia.

FIG 2: Alpha Thal Carrier & Alpha Thal Carrier:

If both partners are carriers then there is a 1 in 4 chance of each pregnancy to produce a child with Alpha Zero thalassaemia major.This is a very serious anaemia that develops in the unborn baby and it can only happen when both parents carry alpha zero thalassaemia.

Genetic counseling is suggested to discuss the several options open for having a healthy family. If after full discussion the couple decides to undertake a pregnancy, the mother can be offered pre-natal testing for the disorder.

FIG 3: Beta Thal Carrier & Beta Thal Carrier:

If couples are tested and one partner proves to be a carrier then there is no danger to their children (same as Fig 1). If both partners are carriers there is a 25% chance of each pregnancy to produce a child with beta thalassaemia major.

Genetic counseling is suggested to discuss the several options open for having a healthy family. If after full discussion the couple decides to undertake a pregnancy, the mother can be offered pre-natal testing for the disorder.

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#AMTF Blood Donation Camp at Amreli Steels (Dhabeji Unit)
April 24, 2019
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Ms. Fariya Zameen (Head of Marketing) & Mr. Muhammad Azam (Head Services Marketing) from Faysal Bank visited #AMTF
April 24, 2019
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#AMTF Thalassemia Awareness Session at Amreli Steels - Dhabeji Unit
April 23, 2019
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#AMTF Blood Donation Camp at Greenwich University, Karachi
April 16, 2019
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#AMTF Blood Donation Camp at PAF-KIET, Nazimabad Campus
April 15, 2019
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#AMTF Blood Donation Camp at Institute of Business Management (IoBM)
April 9, 2019
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Dr. Asim Qidwai, Founder & CEO AMTF had a meeting with High Commissioner Pakistan at Canada Mr. Raza Bashir Tarar in Ottawa
April 4, 2019PRESS RELEASE
April 04, 2019
Dr. Asim Qidwai, Founder & C.E.O of Afzaal Memorial Thalassemia Foundation (AMTF) called on the High Commissioner of Pakistan, Raza Bashir Tarar and briefed him on the work of the Foundation in the field of health care related to children from blood disorder.
The High Commissioner appreciated the plan of the Foundation for conducting awareness sessions with the Pakistani community living abroad. He agreed with the vision of the foundation to deliver the utmost level of passionate care to the patients of thalassemia. The High Commissioner urged the founder for developing synergy among the institutes working in Pakistan on the childhood blood diseases.
Dr. Asim Qidwai also informed the High Commissioner for his drive to include thalassemia awareness and prevention in the curriculum of high schools and colleges of Pakistan.
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